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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYT1
All Species:
30.61
Human Site:
T126
Identified Species:
61.21
UniProt:
P21579
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21579
NP_001129277.1
422
47573
T126
L
K
D
D
D
A
E
T
G
L
T
D
G
E
E
Chimpanzee
Pan troglodytes
XP_001162436
418
47136
S126
I
K
E
K
R
P
C
S
L
G
C
G
K
E
P
Rhesus Macaque
Macaca mulatta
XP_001083913
421
47395
T126
L
K
D
D
D
A
E
T
G
L
T
D
G
E
E
Dog
Lupus familis
XP_539696
422
47627
T126
R
I
P
H
D
A
E
T
G
L
T
D
G
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P46096
421
47399
T125
L
K
D
D
D
A
E
T
G
L
T
D
G
E
E
Rat
Rattus norvegicus
P21707
421
47380
T125
L
K
D
D
D
A
E
T
G
L
T
D
G
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506668
439
49264
T143
L
K
D
D
D
A
E
T
G
L
T
D
G
E
E
Chicken
Gallus gallus
P47191
424
47487
T128
L
K
D
D
D
A
E
T
G
L
T
D
G
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696277
430
48125
M132
D
D
E
E
D
I
D
M
G
I
T
E
E
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21521
474
53246
T176
Q
P
D
M
E
E
L
T
E
N
A
E
E
G
D
Honey Bee
Apis mellifera
NP_001139207
434
48848
T138
Q
P
D
M
E
E
L
T
D
N
A
E
E
P
D
Nematode Worm
Caenorhab. elegans
P34693
441
49885
Q146
E
L
G
D
A
M
E
Q
N
E
K
E
Q
A
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
98.8
98.5
N.A.
97.6
97.8
N.A.
93.3
95.2
N.A.
67.6
N.A.
54.6
61
56.9
N.A.
Protein Similarity:
100
97.1
98.8
98.5
N.A.
98.8
99
N.A.
94.5
97.4
N.A.
81.1
N.A.
66.6
73.7
69.8
N.A.
P-Site Identity:
100
13.3
100
73.3
N.A.
100
100
N.A.
100
100
N.A.
26.6
N.A.
13.3
13.3
20
N.A.
P-Site Similarity:
100
33.3
100
73.3
N.A.
100
100
N.A.
100
100
N.A.
66.6
N.A.
33.3
33.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
59
0
0
0
0
17
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% C
% Asp:
9
9
67
59
67
0
9
0
9
0
0
59
0
0
17
% D
% Glu:
9
0
17
9
17
17
67
0
9
9
0
34
25
67
75
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
67
9
0
9
59
9
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
9
0
0
0
9
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
59
0
9
0
0
0
0
0
0
9
0
9
9
0
% K
% Leu:
50
9
0
0
0
0
17
0
9
59
0
0
0
0
0
% L
% Met:
0
0
0
17
0
9
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
17
0
0
0
0
0
% N
% Pro:
0
17
9
0
0
9
0
0
0
0
0
0
0
9
9
% P
% Gln:
17
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% Q
% Arg:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
75
0
0
67
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _